How does the menstrual cycle affect other health problems? The changing hormone levels throughout the menstrual cycle can also affect other health problems: DERESSION and  ANXIETY DISORDERS. These conditions often overlap with premenstrual syndrome (PMS). Depression and anxiety symptoms are similar to PMS and may get worse before or during your period. ASTHAMA. Your asthma symptoms may be worse during some parts of your cycle. IRRITABLE BOWEL SYNDROME(IBS). IBS causes cramping, bloating, and gas. Your IBS symptoms may get worse right before your period. BLADDER PAIN SYNDROME. Women with bladder pain syndrome are more likely to have painful cramps during PMS. to be continued.........nandini shete.